Depo-Provera is an injectable medicine that prevents pregnancy for up to 3
months with each injection. The popularity of Depo Provera, especially among
more active younger women, is its convenience and the added protection of not
worrying about missing a pill during the monthly cycle. Depo-Provera prevents
pregnancy by preventing ovulation (the release of an egg from the ovary). If
an egg is not released, pregnancy is unlikely.
However, there is a strong relationship between the use of Depo Provera and
the development of osteoporosis. Osteoporosis is a condition that occurs in
women of post menopausal age. As hormone levels in women decline during menopause,
many women experience a reduction in bone density, making them susceptible to
fractures throughout the skeletal system.
Depo-Provera contains a powerful variant of the hormone progestosterone in
time release form and it has been shown to increase the loss of bone density
in women of all ages. This includes teen and young adult women who are in critical
stages of natural bone growth. Studies also show that this bone loss may be
irreversible.
Ten years have passed and the manufacturer of Depo Provera, Pfizer, failed
to do anything until forced by the FDA. The FDA issued an order on November
14, 2004 directing all Depo-Provera packaging and promotional materials to contain
a "black box" warning about the use of Depo-Provera and osteoporosis.
Doctor's have also been advised by the drug manufacturer in a "Dear Doctor"
letter to be aware of the fact that woman who use Depo Provera may lose significant
bone mineral density. Such bone loss is especially significant with increased
duration of use and may not be reversible. The letter goes on to state that
it is unknown if use of Depo Provera during adolescence or early adulthood,
a critical period of bone accretion, will reduce peak bone mass and increase
the risks of hip and joint fractures in later life.
Even though Pfizer acknowledges that the danger of Depo Provera during adolescence
and early adulthood is completely unknown, they continue to actively promote
the product to younger women. They are promoting its convenience, cost effectiveness,
and its ability to protect women from pregnancy without having to remember to
take a pill every day.
If you or a loved one are taking or have taken Depo-Provera and have suffered
a loss of bone density, been diagnosed with Osteoporosis or suffered a bone
fracture please contact our service immediately. We can help put you in touch
Depo Provera attorneys who will review your claim and help you get the compensation
that you deserve.
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